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CMap Candidate Details

Structure:
CMap ID: C04553
Pert ID: BRD-K58114536
Compound Name: rasagiline
Targets: BCL2|MAOB
MoA: monoamine oxidase inhibitor
SMILES: C#CCN[C@@H]1CCc2ccccc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123799 BRD-K58114536 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123839 BRD-K58114536 A549 0.37 uM 24 h 0.0 0.0 0.0 -0.42 -1.41 2.02
123873 BRD-K58114536 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123904 BRD-K58114536 HEK293 1.11 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.22
123945 BRD-K58114536 HELA 3.33 uM 24 h 0.23 0.95 0.06 0.0 0.0 0.0
124005 BRD-K58114536 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124058 BRD-K58114536 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124098 BRD-K58114536 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.31
124126 BRD-K58114536 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124187 BRD-K58114536 THP1 0.37 uM 24 h -0.29 -1.21 0.59 0.0 0.0 0.0
124239 BRD-K58114536 YAPC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132229 BRD-K58114536 HT29 0.03 uM 24 h -0.27 -1.14 0.42 -0.37 -1.23 1.25
132298 BRD-K58114536 PC3 0.03 uM 24 h -0.22 -0.92 0.06 0.22 0.77 0.06
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).