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CMap Candidate Details

Structure:
CMap ID: C04560
Pert ID: BRD-M39350793
Compound Name: reboxetine
Targets: SLC6A2
MoA: adrenergic receptor antagonist
SMILES: CCOc1ccccc1O[C@@H]([C@H]1CNCCO1)c1ccccc1.CCOc1ccccc1O[C@H]([C@@H]1CNCCO1)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123231 BRD-M39350793 A375 0.125 uM 24 h 0.19 0.8 0.0 0.0 0.0 0.0
123287 BRD-M39350793 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123490 BRD-M39350793 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131546 BRD-M39350793 A549 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131582 BRD-M39350793 HA1E 0.74 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
131656 BRD-M39350793 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131684 BRD-M39350793 HT29 0.25 uM 24 h -0.24 -1.01 0.16 0.0 0.0 0.0
131718 BRD-M39350793 HUVEC 0.74 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.21
131771 BRD-M39350793 JURKAT 0.74 uM 24 h 0.22 0.94 0.05 0.0 0.0 0.0
131819 BRD-M39350793 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.12
131851 BRD-M39350793 MCF??7.00 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131887 BRD-M39350793 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 0.22 0.77 0.06
131915 BRD-M39350793 PC3 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131931 BRD-M39350793 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).