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CMap Candidate Details

Structure:
CMap ID: C04563
Pert ID: BRD-A78341343
Compound Name: regadenoson
Targets: ADORA1|ADORA2A|ADORA2B|ADORA3
MoA: adenosine receptor agonist
SMILES: CNC(=O)c1cnn(c1)-c1nc(N)c2ncn([C@@H]3O[C@H](CO)C(O)C3O)c2n1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127031 BRD-A78341343 A375 10 uM 24 h 0.0 0.0 0.0 0.32 1.15 0.88
127115 BRD-A78341343 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127150 BRD-A78341343 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127291 BRD-A78341343 THP1 3.33 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.35
127326 BRD-A78341343 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135058 BRD-A78341343 A549 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135092 BRD-A78341343 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135115 BRD-A78341343 HEK293 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135185 BRD-A78341343 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135217 BRD-A78341343 MCF10A 0.25 uM 24 h -0.19 -0.78 0.0 -0.23 -0.77 0.08
135236 BRD-A78341343 MCF??7.00 2.22 uM 24 h 0.29 1.23 0.5 0.0 0.0 0.0
135283 BRD-A78341343 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.2
135301 BRD-A78341343 PC3 0.74 uM 24 h 0.0 0.0 0.0 0.28 1.01 0.44
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).