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CMap Candidate Details

Structure:
CMap ID: C00457
Pert ID: BRD-K36269323
Compound Name: asymmetrical-dimethylarginine
Targets: NOS2|NOS3
MoA: nitric oxide synthase inhibitor
SMILES: CN(C)C(=N)NCCC[C@H](N)C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121755 BRD-K36269323 HELA 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121784 BRD-K36269323 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129748 BRD-K36269323 A375 2.22 uM 24 h 0.22 0.92 0.04 0.37 1.32 1.68
129781 BRD-K36269323 HA1E 0.01 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.77
129812 BRD-K36269323 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129938 BRD-K36269323 MCF10A 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129988 BRD-K36269323 MCF??7.00 0.08 uM 24 h -0.29 -1.2 0.55 0.0 0.0 0.0
130023 BRD-K36269323 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.21
130075 BRD-K36269323 PC3 0.25 uM 24 h -0.25 -1.03 0.2 0.33 1.17 0.93
130096 BRD-K36269323 THP1 0.01 uM 24 h -0.26 -1.1 0.34 0.0 0.0 0.0
130146 BRD-K36269323 YAPC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).