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CMap Candidate Details

Structure:
CMap ID: C04570
Pert ID: BRD-K54094468
Compound Name: remoxipride
Targets: DRD2|DRD3|DRD4|HTR2A|SIGMAR1
MoA: dopamine receptor antagonist
SMILES: CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3038 BRD-K54094468 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.79 0.1
3231 BRD-K54094468 HCC515 10 uM 24 h -0.22 -0.91 0.05 -0.24 -0.8 0.12
3970 BRD-K54094468 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39144 BRD-K54094468 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39331 BRD-K54094468 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39713 BRD-K54094468 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40017 BRD-K54094468 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40289 BRD-K54094468 HT29 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.22 1.24
40480 BRD-K54094468 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40827 BRD-K54094468 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41134 BRD-K54094468 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41469 BRD-K54094468 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52306 BRD-K54094468 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91116 BRD-K54094468 HUH7 8 uM 72 h 0.0 0.0 0.0 -0.25 -0.84 0.18
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).