CMap Candidate Details
Structure:
| CMap ID: | C04577 |
| Pert ID: | BRD-K76210423 |
| Compound Name: | resiquimod |
| Targets: | TLR7|TLR8 |
| MoA: | toll-like receptor agonist |
| SMILES: | CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 127362 | BRD-K76210423 | A375 | 3.33 uM | 24 h | -0.19 | -0.78 | 0.0 | 0.27 | 0.94 | 0.3 |
| 127398 | BRD-K76210423 | A549 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.78 | 0.1 |
| 127436 | BRD-K76210423 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127617 | BRD-K76210423 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127653 | BRD-K76210423 | THP1 | 10 uM | 24 h | -0.26 | -1.08 | 0.29 | -0.31 | -1.06 | 0.72 |
| 127698 | BRD-K76210423 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.23 | 0.82 | 0.1 |
| 135374 | BRD-K76210423 | HELA | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135413 | BRD-K76210423 | HT29 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135444 | BRD-K76210423 | MCF10A | 2.22 uM | 24 h | -0.2 | -0.83 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135478 | BRD-K76210423 | MCF??7.00 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |