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CMap Candidate Details

Structure:
CMap ID: C04578
Pert ID: BRD-K28822270
Compound Name: resminostat
Targets: HDAC1|HDAC3|HDAC6|HDAC8
MoA: HDAC inhibitor
SMILES: CN(C)Cc1ccc(cc1)S(=O)(=O)n1ccc(c1)\C=C\C(=O)NO
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95475 BRD-K28822270 U2OS 10 uM 6 h 0.17 0.69 0.0 0.0 0.0 0.0
97260 BRD-K28822270 HAP1 0.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121886 BRD-K28822270 A375 1.11 uM 24 h -0.18 -0.76 0.0 -0.22 -0.75 0.07
121952 BRD-K28822270 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122036 BRD-K28822270 HUVEC 3.33 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.09
122087 BRD-K28822270 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122101 BRD-K28822270 MCF??7.00 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122212 BRD-K28822270 YAPC 3.33 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
130195 BRD-K28822270 A549 2.22 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.58
130218 BRD-K28822270 HA1E 2.22 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.03
130279 BRD-K28822270 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130313 BRD-K28822270 HT29 0.74 uM 24 h 0.24 1.0 0.11 -0.25 -0.86 0.21
130338 BRD-K28822270 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130443 BRD-K28822270 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130474 BRD-K28822270 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130491 BRD-K28822270 THP1 2.22 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).