CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04584
Pert ID:	BRD-K89917372
Compound Name:	retigabine
Targets:	KCNQ1\|KCNQ2\|KCNQ3\|KCNQ4\|KCNQ5
MoA:	potassium channel activator
SMILES:	CCOC(=O)Nc1ccc(NCc2ccc(F)cc2)cc1N
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
127736	BRD-K89917372	A375	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127779	BRD-K89917372	A549	1.11 uM	24 h	0.0	0.0	0.0	0.21	0.76	0.05
127819	BRD-K89917372	HA1E	10 uM	24 h	0.0	0.0	0.0	0.32	1.15	0.88
127859	BRD-K89917372	HEK293	0.125 uM	24 h	0.0	0.0	0.0	0.23	0.8	0.08
127933	BRD-K89917372	HUVEC	10 uM	24 h	0.23	0.95	0.06	0.0	0.0	0.0
127987	BRD-K89917372	MCF10A	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128025	BRD-K89917372	MCF??7.00	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128047	BRD-K89917372	PC3	10 uM	24 h	0.0	0.0	0.0	-0.35	-1.19	1.15
135560	BRD-K89917372	HELA	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135607	BRD-K89917372	HT29	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135651	BRD-K89917372	JURKAT	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135741	BRD-K89917372	YAPC	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary