CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04586
Pert ID:	BRD-K22429181
Compound Name:	retinol
Targets:	ALDH1A1\|ALDH1A2\|ALDH1A3\|DHRS3\|DHRS4\|LRAT\|NR2C2\|RBP1\|RBP3\|RDH11\|RDH12\|RDH13\|RDH14\|RDH5\|RDH8\|RETSAT\|RHO\|RLBP1\|RXRA\|RXRB\|RXRG
MoA:	retinoid receptor ligand
SMILES:	CC(\C=C\C=C(C)\C=C\C1=C(C)CCCC1(C)C)=C/CO
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
33587	BRD-K22429181	A375	10 uM	6 h	0.0	0.0	0.0	-0.33	-1.11	0.9
34062	BRD-K22429181	ASC	10 uM	24 h	0.0	0.0	0.0	-0.31	-1.05	0.7
34328	BRD-K22429181	HA1E	10 uM	6 h	0.3	1.25	0.54	0.0	0.0	0.0
34578	BRD-K22429181	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
34846	BRD-K22429181	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
35110	BRD-K22429181	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
35303	BRD-K22429181	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
36066	BRD-K22429181	PC3	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
36221	BRD-K22429181	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
36515	BRD-K22429181	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
36788	BRD-K22429181	VCAP	10 uM	24 h	0.0	0.0	0.0	-0.28	-0.94	0.37
96121	BRD-K22429181	A549	10 uM	24 h	-0.29	-1.22	0.61	-0.26	-0.86	0.21
98874	BRD-K22429181	NEU	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99223	BRD-K22429181	NPC	10 uM	6 h	-0.24	-0.99	0.13	0.0	0.0	0.0

Summary