CMap Candidate Details
Structure:
| CMap ID: | C04617 |
| Pert ID: | BRD-K28346421 |
| Compound Name: | rifapentine |
| Targets: | CYP2C8|CYP2C9|CYP3A4 |
| MoA: | RNA polymerase inhibitor |
| SMILES: | CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C2=O)c2c(O)c(\C=N\N4CCN(CC4)C4CCCC4)c(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(O)c2c(O)c3C |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 19002 | BRD-K28346421 | A375 | 10 uM | 6 h | -0.27 | -1.12 | 0.39 | 0.0 | 0.0 | 0.0 |
| 19438 | BRD-K28346421 | A549 | 10 uM | 6 h | -0.28 | -1.19 | 0.52 | -0.24 | -0.81 | 0.13 |
| 19650 | BRD-K28346421 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 19975 | BRD-K28346421 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 20307 | BRD-K28346421 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 20631 | BRD-K28346421 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.1 | 0.86 |
| 20883 | BRD-K28346421 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.33 | 1.17 | 0.92 |
| 21227 | BRD-K28346421 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 21729 | BRD-K28346421 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |