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CMap Candidate Details

Structure:
CMap ID: C04621
Pert ID: BRD-K06240250
Compound Name: rilpivirine
Targets: NR1I2|SCN10A
MoA: non-nucleoside reverse transcriptase inhibitor
SMILES: Cc1cc(\C=C\C#N)cc(C)c1Nc1ccnc(Nc2ccc(cc2)C#N)n1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122542 BRD-K06240250 A375 10 uM 24 h 0.0 0.0 0.0 0.21 0.73 0.03
122599 BRD-K06240250 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122631 BRD-K06240250 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122657 BRD-K06240250 HELA 10 uM 24 h 0.26 1.07 0.19 -0.4 -1.35 2.01
122679 BRD-K06240250 HT29 10 uM 24 h 0.2 0.82 0.0 0.0 0.0 0.0
122715 BRD-K06240250 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122750 BRD-K06240250 MCF??7.00 0.04 uM 24 h 0.26 1.08 0.21 0.0 0.0 0.0
122791 BRD-K06240250 PC3 10 uM 24 h -0.21 -0.88 0.03 0.0 0.0 0.0
122813 BRD-K06240250 YAPC 0.04 uM 24 h -0.19 -0.78 0.0 0.0 0.0 0.0
130883 BRD-K06240250 A549 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131037 BRD-K06240250 HUVEC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131115 BRD-K06240250 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).