CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04622
Pert ID:	BRD-K21283037
Compound Name:	riluzole
Targets:	KCNK10\|KCNK2\|KCNK4\|KCNN4\|SCN10A\|SCN11A\|SCN1A\|SCN2A\|SCN3A\|SCN4A\|SCN5A\|SCN7A\|SCN8A\|SCN9A\|SLC7A11
MoA:	glutamate inhibitor
SMILES:	Nc1nc2ccc(OC(F)(F)F)cc2s1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1461	BRD-K21283037	NPC	4 uM	24 h	0.0	0.0	0.0	-0.29	-0.98	0.5
3344	BRD-K21283037	HCC515	10 uM	6 h	-0.23	-0.98	0.12	-0.36	-1.2	1.21
3749	BRD-K21283037	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
24564	BRD-K21283037	A549	10 uM	24 h	0.0	0.0	0.0	0.32	1.13	0.84
39648	BRD-K21283037	ASC	10 uM	24 h	0.0	0.0	0.0	0.24	0.85	0.15
39964	BRD-K21283037	HEPG2	10 uM	6 h	0.0	0.0	0.0	-0.38	-1.28	1.45
41402	BRD-K21283037	SKB	10 uM	24 h	0.0	0.0	0.0	-0.24	-0.81	0.14
91174	BRD-K21283037	HUH7	15 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
98355	BRD-K21283037	NEU	10 uM	24 h	0.23	0.97	0.08	0.0	0.0	0.0
99741	BRD-K21283037	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
121369	BRD-K21283037	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121387	BRD-K21283037	HA1E	10 uM	24 h	0.0	0.0	0.0	-0.25	-0.83	0.16
121413	BRD-K21283037	HELA	10 uM	24 h	0.24	0.99	0.1	-0.39	-1.33	1.71
121440	BRD-K21283037	HT29	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121463	BRD-K21283037	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121481	BRD-K21283037	PC3	10 uM	24 h	0.0	0.0	0.0	-0.33	-1.1	0.87
121518	BRD-K21283037	YAPC	0.37 uM	24 h	0.0	0.0	0.0	-0.28	-0.95	0.39

Summary