CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04626
Pert ID:	BRD-K13296708
Compound Name:	rimonabant
Targets:	CNR1\|GPR55
MoA:	cannabinoid receptor antagonist
SMILES:	Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
98577	BRD-K13296708	NEU	10 uM	6 h	0.27	1.12	0.27	0.0	0.0	0.0
98674	BRD-K13296708	NPC	10 uM	6 h	0.0	0.0	0.0	-0.32	-1.08	0.8
122252	BRD-K13296708	A375	1.11 uM	24 h	0.0	0.0	0.0	-0.28	-0.94	0.37
122315	BRD-K13296708	HEK293	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122330	BRD-K13296708	HELA	10 uM	24 h	0.0	0.0	0.0	-0.25	-0.85	0.2
122362	BRD-K13296708	MCF10A	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122389	BRD-K13296708	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122440	BRD-K13296708	PC3	10 uM	24 h	-0.27	-1.11	0.36	0.45	1.6	2.37
122475	BRD-K13296708	THP1	10 uM	24 h	0.0	0.0	0.0	0.28	0.98	0.37
130555	BRD-K13296708	A549	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130590	BRD-K13296708	HA1E	0.74 uM	24 h	-0.2	-0.82	0.0	0.0	0.0	0.0
130707	BRD-K13296708	HT29	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130783	BRD-K13296708	MDAMB231	0.01 uM	24 h	0.26	1.08	0.21	0.0	0.0	0.0
130836	BRD-K13296708	YAPC	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary