CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04633
Pert ID:	BRD-K53857191
Compound Name:	risperidone
Targets:	ADRA1A\|ADRA1B\|ADRA1D\|ADRA2A\|ADRA2B\|ADRA2C\|DRD1\|DRD2\|DRD3\|DRD4\|HRH1\|HTR1A\|HTR1B\|HTR1D\|HTR1E\|HTR1F\|HTR2A\|HTR2C\|HTR6\|HTR7
MoA:	dopamine receptor antagonist; serotonin receptor antagonist
SMILES:	Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1433	BRD-K53857191	NPC	25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
1923	BRD-K53857191	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
24787	BRD-K53857191	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
25388	BRD-K53857191	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
42106	BRD-K53857191	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
42392	BRD-K53857191	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
42712	BRD-K53857191	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
43880	BRD-K53857191	PHH	10 uM	24 h	0.0	0.0	0.0	0.2	0.72	0.02
44137	BRD-K53857191	SKB	10 uM	24 h	0.26	1.09	0.23	0.41	1.44	2.21
98397	BRD-K53857191	NEU	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99649	BRD-K53857191	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
124355	BRD-K53857191	HELA	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124422	BRD-K53857191	JURKAT	1.11 uM	24 h	0.0	0.0	0.0	-0.32	-1.06	0.73
124452	BRD-K53857191	MCF10A	10 uM	24 h	0.0	0.0	0.0	-0.27	-0.93	0.34
124491	BRD-K53857191	MDAMB231	3.33 uM	24 h	-0.22	-0.93	0.07	-0.21	-0.71	0.03
124520	BRD-K53857191	PC3	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124551	BRD-K53857191	YAPC	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132333	BRD-K53857191	A375	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132426	BRD-K53857191	HEK293	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132466	BRD-K53857191	HT29	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132525	BRD-K53857191	MCF??7.00	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132610	BRD-K53857191	THP1	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary