CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04635
Pert ID:	BRD-K40887525
Compound Name:	ritanserin
Targets:	ADRA1A\|ADRA1B\|ADRA1D\|HTR1A\|HTR1B\|HTR1D\|HTR2A\|HTR2B\|HTR2C\|HTR5A\|HTR6\|HTR7
MoA:	serotonin receptor antagonist
SMILES:	Cc1nc2sccn2c(=O)c1CCN1CCC(CC1)=C(c1ccc(F)cc1)c1ccc(F)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5328	BRD-K40887525	HA1E	10 uM	24 h	0.0	0.0	0.0	-0.33	-1.1	0.88
5626	BRD-K40887525	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
5913	BRD-K40887525	HEPG2	10 uM	6 h	0.0	0.0	0.0	-0.21	-0.72	0.04
6278	BRD-K40887525	PC3	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
6342	BRD-K40887525	VCAP	10 uM	24 h	-0.16	-0.66	0.0	0.26	0.92	0.25
37154	BRD-K40887525	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
37384	BRD-K40887525	A549	10 uM	6 h	0.22	0.92	0.04	0.0	0.0	0.0
37653	BRD-K40887525	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
38081	BRD-K40887525	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
38203	BRD-K40887525	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
38478	BRD-K40887525	NPC	10 uM	24 h	0.0	0.0	0.0	-0.26	-0.87	0.22
38718	BRD-K40887525	PHH	10 uM	24 h	0.2	0.82	0.0	-0.25	-0.85	0.19
38952	BRD-K40887525	SKB	10 uM	24 h	-0.25	-1.03	0.2	0.0	0.0	0.0

Summary