CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00465
Pert ID:	BRD-A20239487
Compound Name:	atenolol-(+/-)
Targets:	ADRB1\|ADRB2
MoA:	adrenergic receptor antagonist
SMILES:	CC(C)NCC(O)COc1ccc(CC(N)=O)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
50285	BRD-A20239487	HCC515	10 uM	6 h	0.0	0.0	0.0	0.31	1.11	0.72
51092	BRD-A20239487	VCAP	10 uM	6 h	0.0	0.0	0.0	-0.22	-0.73	0.05
90780	BRD-A20239487	HPTEC	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
127008	BRD-A20239487	A375	10 uM	24 h	-0.23	-0.97	0.11	0.28	0.98	0.38
127062	BRD-A20239487	HEK293	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127127	BRD-A20239487	HT29	0.37 uM	24 h	-0.23	-0.96	0.1	0.35	1.25	1.29
127176	BRD-A20239487	MCF10A	0.04 uM	24 h	0.24	1.02	0.13	0.0	0.0	0.0
127198	BRD-A20239487	MCF??7.00	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127225	BRD-A20239487	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127266	BRD-A20239487	THP1	10 uM	24 h	0.0	0.0	0.0	0.28	1.0	0.42
135028	BRD-A20239487	A549	0.03 uM	24 h	-0.35	-1.45	1.43	0.33	1.16	0.9
135072	BRD-A20239487	HA1E	0.03 uM	24 h	0.2	0.85	0.01	0.0	0.0	0.0
135124	BRD-A20239487	HELA	2.22 uM	24 h	-0.3	-1.27	0.74	0.2	0.7	0.01
135160	BRD-A20239487	JURKAT	0.25 uM	24 h	0.37	1.53	1.45	0.0	0.0	0.0
135245	BRD-A20239487	MDAMB231	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135317	BRD-A20239487	YAPC	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary