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CMap Candidate Details

Structure:
CMap ID: C04665
Pert ID: BRD-K58299615
Compound Name: Ro-90-7501
Targets: APP
MoA:
SMILES: Nc1ccc(cc1)-c1nc2ccc(cc2[nH]1)-c1nc2ccc(N)cc2[nH]1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6789 BRD-K58299615 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7018 BRD-K58299615 A549 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.54
7346 BRD-K58299615 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7696 BRD-K58299615 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7901 BRD-K58299615 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8219 BRD-K58299615 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8399 BRD-K58299615 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
53404 BRD-K58299615 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
53596 BRD-K58299615 HUH7 10 uM 6 h -0.26 -1.07 0.28 0.27 0.94 0.29
53676 BRD-K58299615 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90323 BRD-K58299615 VCAP 10 uM 24 h -0.16 -0.68 0.0 0.26 0.92 0.25
99697 BRD-K58299615 U2OS 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.2 1.21
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).