CMap Candidate Details
Structure:
| CMap ID: | C04673 |
| Pert ID: | BRD-K75516118 |
| Compound Name: | rolipram-R(-) |
| Targets: | PDE4A|PDE4B|PDE4C|PDE4D|PDE5A |
| MoA: | phosphodiesterase inhibitor |
| SMILES: | COc1ccc(cc1OC1CCCC1)[C@@H]1CNC(=O)C1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 97034 | BRD-K75516118 | A375 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.28 | 0.99 | 0.39 |
| 97111 | BRD-K75516118 | PC3 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.1 | 0.87 |
| 98825 | BRD-K75516118 | NPC | 10 uM | 6 h | -0.19 | -0.8 | 0.0 | 0.0 | 0.0 | 0.0 |
| 99084 | BRD-K75516118 | NEU | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 99464 | BRD-K75516118 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.21 | -0.71 | 0.03 |