CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04679
Pert ID:	BRD-K15933101
Compound Name:	ropinirole
Targets:	ADRA2A\|ADRA2B\|ADRA2C\|DRD1\|DRD2\|DRD3\|DRD4\|DRD5\|HTR1A\|HTR1B\|HTR1D\|HTR2A\|HTR2B\|HTR2C
MoA:	dopamine receptor agonist
SMILES:	CCCN(CCC)CCc1cccc2NC(=O)Cc12
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5586	BRD-K15933101	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
5889	BRD-K15933101	HEPG2	10 uM	6 h	0.0	0.0	0.0	-0.27	-0.9	0.29
6412	BRD-K15933101	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
37129	BRD-K15933101	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
37271	BRD-K15933101	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
37605	BRD-K15933101	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
38186	BRD-K15933101	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
38437	BRD-K15933101	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
38919	BRD-K15933101	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120428	BRD-K15933101	PC3	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120458	BRD-K15933101	YAPC	1.11 uM	24 h	0.27	1.11	0.25	0.2	0.71	0.02
128902	BRD-K15933101	HA1E	0.74 uM	24 h	0.16	0.65	0.0	0.0	0.0	0.0
128921	BRD-K15933101	HELA	2.22 uM	3 h	0.0	0.0	0.0	0.0	0.0	0.0
128937	BRD-K15933101	HT29	0.08 uM	24 h	0.0	0.0	0.0	0.24	0.86	0.15

Summary