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CMap Candidate Details

Structure:
CMap ID: C00468
Pert ID: BRD-K39252998
Compound Name: atipamezole
Targets:
MoA: adrenergic receptor antagonist
SMILES: CCC1(Cc2ccccc2C1)c1cnc[nH]1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96318 BRD-K39252998 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96389 BRD-K39252998 PC3 10 uM 24 h -0.17 -0.73 0.0 -0.38 -1.29 1.5
123363 BRD-K39252998 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.31 1.08 0.66
123395 BRD-K39252998 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 0.34 1.2 1.07
123489 BRD-K39252998 YAPC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131545 BRD-K39252998 A549 0.25 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
131581 BRD-K39252998 HA1E 0.25 uM 24 h -0.18 -0.74 0.0 -0.31 -1.03 0.64
131622 BRD-K39252998 HEK293 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131655 BRD-K39252998 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131683 BRD-K39252998 HT29 2.22 uM 24 h 0.23 0.96 0.07 -0.26 -0.87 0.23
131717 BRD-K39252998 HUVEC 2.22 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
131770 BRD-K39252998 JURKAT 0.25 uM 24 h 0.27 1.13 0.28 -0.28 -0.94 0.39
131850 BRD-K39252998 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.4
131930 BRD-K39252998 THP1 0.03 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.48
136408 BRD-K39252998 SHSY5Y 3.33 uM 24 h 0.25 1.02 0.13 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).