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CMap Candidate Details

Structure:
CMap ID: C04681
Pert ID: BRD-K03384561
Compound Name: roquinimex
Targets:
MoA: angiogenesis inhibitor; tumor necrosis factor production inhibitor
SMILES: CN(C(=O)c1c(O)c2ccccc2n(C)c1=O)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4341 BRD-K03384561 HCC515 10 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.7
5021 BRD-K03384561 VCAP 10 uM 6 h 0.17 0.71 0.0 0.0 0.0 0.0
44817 BRD-K03384561 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45932 BRD-K03384561 NPC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.56
46251 BRD-K03384561 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46567 BRD-K03384561 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122923 BRD-K03384561 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122955 BRD-K03384561 HELA 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122995 BRD-K03384561 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123048 BRD-K03384561 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 0.23 0.83 0.11
123138 BRD-K03384561 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123208 BRD-K03384561 THP1 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
131222 BRD-K03384561 A375 0.01 uM 24 h 0.0 0.0 0.0 0.25 0.9 0.22
131264 BRD-K03384561 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131295 BRD-K03384561 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131385 BRD-K03384561 HUVEC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131420 BRD-K03384561 MCF10A 0.74 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.05
131449 BRD-K03384561 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131477 BRD-K03384561 PC3 0.08 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
131518 BRD-K03384561 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.18 0.63 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).