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CMap Candidate Details

Structure:
CMap ID: C04687
Pert ID: BRD-K20313525
Compound Name: rosmarinic-acid
Targets: MCL1|TYR
MoA: GABA transaminase inhibitor
SMILES: OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c1ccc(O)c(O)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2849 BRD-K20313525 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.43 -1.44 15.35
3159 BRD-K20313525 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.12
3746 BRD-K20313525 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44546 BRD-K20313525 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44894 BRD-K20313525 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45197 BRD-K20313525 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45464 BRD-K20313525 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45787 BRD-K20313525 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.37
46012 BRD-K20313525 NPC 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.18
46330 BRD-K20313525 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46646 BRD-K20313525 SKB 10 uM 24 h -0.2 -0.85 0.01 -0.27 -0.91 0.31
97122 BRD-K20313525 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97190 BRD-K20313525 PC3 3.33 uM 24 h 0.27 1.11 0.25 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).