CMap Candidate Details
Structure:
| CMap ID: | C04692 |
| Pert ID: | BRD-K35719256 |
| Compound Name: | rotundine |
| Targets: | DRD1|DRD2|DRD3|HTR1A |
| MoA: | serotonin receptor agonist |
| SMILES: | COc1cc2CCN3Cc4c(C[C@H]3c2cc1OC)ccc(OC)c4OC |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120574 | BRD-K35719256 | A549 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120679 | BRD-K35719256 | HT29 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.0 | 0.55 |
| 120732 | BRD-K35719256 | JURKAT | 1.11 uM | 24 h | -0.37 | -1.54 | 1.43 | 0.0 | 0.0 | 0.0 |
| 120789 | BRD-K35719256 | PC3 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120840 | BRD-K35719256 | YAPC | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.06 | 0.6 |
| 128994 | BRD-K35719256 | A375 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129011 | BRD-K35719256 | HA1E | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.95 | 0.41 |
| 129041 | BRD-K35719256 | HELA | 0.01 uM | 3 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.97 | 0.45 |
| 129067 | BRD-K35719256 | MCF??7.00 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.21 | -0.7 | 0.03 |
| 136450 | BRD-K35719256 | SHSY5Y | 0.37 uM | 24 h | 0.21 | 0.87 | 0.01 | 0.0 | 0.0 | 0.0 |