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CMap Candidate Details

Structure:
CMap ID: C04705
Pert ID: BRD-K80725821
Compound Name: RS-16566
Targets:
MoA: serotonin receptor antagonist
SMILES: CC(C)n1cnc2c(cc(Cl)cc12)C(=O)N[C@H]1CN2CCC1CC2
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2926 BRD-K80725821 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
3396 BRD-K80725821 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3545 BRD-K80725821 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3981 BRD-K80725821 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39187 BRD-K80725821 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39496 BRD-K80725821 A549 10 uM 6 h 0.0 0.0 0.0 0.2 0.69 0.01
39777 BRD-K80725821 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40070 BRD-K80725821 HEPG2 10 uM 6 h 0.16 0.65 0.0 -0.21 -0.7 0.03
40334 BRD-K80725821 HT29 10 uM 6 h -0.22 -0.92 0.06 -0.25 -0.84 0.17
40641 BRD-K80725821 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41196 BRD-K80725821 NPC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.68
41535 BRD-K80725821 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).