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CMap Candidate Details

Structure:
CMap ID: C04707
Pert ID: BRD-K01868942
Compound Name: RS-23597-190
Targets: HTR4
MoA: serotonin receptor antagonist
SMILES: COc1cc(N)c(Cl)cc1C(=O)OCCCN1CCCCC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8895 BRD-K01868942 A375 150 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9163 BRD-K01868942 A549 150 uM 6 h -0.2 -0.85 0.01 0.0 0.0 0.0
9637 BRD-K01868942 H1299 150 uM 6 h 0.0 0.0 0.0 0.22 0.78 0.07
9887 BRD-K01868942 HA1E 150 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10133 BRD-K01868942 HCC515 150 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10435 BRD-K01868942 HCT116 150 uM 6 h 0.18 0.76 0.0 0.3 1.08 0.65
10708 BRD-K01868942 HEPG2 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10926 BRD-K01868942 HT29 150 uM 24 h -0.25 -1.03 0.2 0.27 0.95 0.32
11145 BRD-K01868942 MCF??7.00 150 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11386 BRD-K01868942 NCIH2073 150 uM 6 h -0.21 -0.86 0.02 0.0 0.0 0.0
11691 BRD-K01868942 NCIH508 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11958 BRD-K01868942 NCIH596 150 uM 6 h -0.3 -1.25 0.71 0.0 0.0 0.0
12449 BRD-K01868942 PC3 150 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12703 BRD-K01868942 SW480 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13183 BRD-K01868942 U937 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13563 BRD-K01868942 VCAP 150 uM 6 h 0.0 0.0 0.0 0.31 1.11 0.72
99965 BRD-K01868942 U2OS 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.2 1.22
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).