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CMap Candidate Details

Structure:
CMap ID: C04709
Pert ID: BRD-K26160755
Compound Name: RS-45041-190
Targets:
MoA: imidazoline receptor agonist
SMILES: Clc1cccc2CN(Cc12)C1=NCCN1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4086 BRD-K26160755 HA1E 10 uM 24 h -0.25 -1.02 0.19 -0.3 -1.02 0.59
4398 BRD-K26160755 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4792 BRD-K26160755 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4911 BRD-K26160755 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39107 BRD-K26160755 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39436 BRD-K26160755 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39654 BRD-K26160755 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39970 BRD-K26160755 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40247 BRD-K26160755 HT29 10 uM 6 h 0.0 0.0 0.0 0.26 0.9 0.22
40602 BRD-K26160755 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.21 -0.72 0.04
40775 BRD-K26160755 NEU 10 uM 24 h 0.0 0.0 0.0 0.23 0.83 0.12
41076 BRD-K26160755 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41408 BRD-K26160755 SKB 10 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.69
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).