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CMap Candidate Details

Structure:
CMap ID: C04718
Pert ID: BRD-K00234327
Compound Name: RU-24969
Targets: HTR1A|HTR1B|HTR1D|HTR2A|HTR2B|HTR2C|HTR5A|HTR6
MoA: serotonin receptor agonist
SMILES: COc1ccc2[nH]cc(C3=CCNCC3)c2c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5293 BRD-K00234327 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5748 BRD-K00234327 HCC515 10 uM 6 h 0.0 0.0 0.0 0.33 1.18 0.99
5872 BRD-K00234327 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.34 -1.16 1.09
22034 BRD-K00234327 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22225 BRD-K00234327 A549 10 uM 6 h -0.27 -1.13 0.41 0.0 0.0 0.0
23954 BRD-K00234327 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24276 BRD-K00234327 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44805 BRD-K00234327 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45394 BRD-K00234327 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45757 BRD-K00234327 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46242 BRD-K00234327 PHH 10 uM 24 h -0.23 -0.94 0.08 0.0 0.0 0.0
46556 BRD-K00234327 SKB 10 uM 24 h -0.24 -0.99 0.13 0.32 1.14 0.85
98206 BRD-K00234327 NPC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
98565 BRD-K00234327 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).