CMap Candidate Details
Structure:
| CMap ID: | C00472 |
| Pert ID: | BRD-K20141153 |
| Compound Name: | atomoxetine |
| Targets: | GRIN1|GRIN2A|GRIN2B|GRIN2C|GRIN2D|GRIN3A|GRIN3B|SLC6A2|SLC6A3|SLC6A4 |
| MoA: | norepinephrine transporter inhibitor |
| SMILES: | CNCC[C@@H](Oc1ccccc1C)c1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 2994 | BRD-K20141153 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.29 | 1.01 | 0.44 |
| 3157 | BRD-K20141153 | HCC515 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.93 | 0.27 |
| 3744 | BRD-K20141153 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 44545 | BRD-K20141153 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.78 | 0.09 |
| 45196 | BRD-K20141153 | HEPG2 | 10 uM | 6 h | -0.25 | -1.06 | 0.25 | 0.0 | 0.0 | 0.0 |
| 120857 | BRD-K20141153 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120940 | BRD-K20141153 | HEK293 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120997 | BRD-K20141153 | HELA | 0.04 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121032 | BRD-K20141153 | MCF??7.00 | 0.125 uM | 24 h | 0.22 | 0.91 | 0.03 | 0.0 | 0.0 | 0.0 |
| 121098 | BRD-K20141153 | YAPC | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.1 | 0.86 |
| 129184 | BRD-K20141153 | HT29 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.97 | 0.46 |
| 129215 | BRD-K20141153 | PC3 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |