CMap Candidate Details
Structure:
| CMap ID: | C04725 |
| Pert ID: | BRD-K20079257 |
| Compound Name: | rufinamide |
| Targets: | GRM5|SCN10A|SCN11A|SCN1A|SCN2A|SCN3A|SCN4A|SCN5A|SCN7A|SCN8A|SCN9A |
| MoA: | voltage-gated sodium channel blocker |
| SMILES: | NC(=O)c1cn(Cc2c(F)cccc2F)nn1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121407 | BRD-K20079257 | HELA | 0.04 uM | 24 h | 0.18 | 0.77 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121511 | BRD-K20079257 | YAPC | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129405 | BRD-K20079257 | A375 | 0.01 uM | 24 h | 0.26 | 1.09 | 0.23 | 0.35 | 1.25 | 1.28 |
| 129435 | BRD-K20079257 | HA1E | 0.01 uM | 24 h | 0.18 | 0.76 | 0.0 | -0.31 | -1.03 | 0.63 |
| 129491 | BRD-K20079257 | HT29 | 0.25 uM | 24 h | 0.23 | 0.98 | 0.09 | -0.23 | -0.79 | 0.1 |
| 129520 | BRD-K20079257 | MCF??7.00 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129554 | BRD-K20079257 | PC3 | 0.01 uM | 24 h | 0.23 | 0.95 | 0.07 | 0.0 | 0.0 | 0.0 |