CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04726
Pert ID:	BRD-K62374253
Compound Name:	rufloxacin
Targets:
MoA:	bacterial DNA gyrase inhibitor
SMILES:	CN1CCN(CC1)c1c(F)cc2c3c1SCCn3cc(C(O)=O)c2=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
24464	BRD-K62374253	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
24594	BRD-K62374253	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
24797	BRD-K62374253	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
24932	BRD-K62374253	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
25175	BRD-K62374253	PC3	10 uM	24 h	0.23	0.94	0.06	0.0	0.0	0.0
25401	BRD-K62374253	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
52066	BRD-K62374253	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	-0.34	-1.13	0.98
91445	BRD-K62374253	HUH7	10 uM	72 h	-0.21	-0.86	0.02	0.3	1.07	0.62

Summary