CMap Candidate Details
Structure:
| CMap ID: | C04731 |
| Pert ID: | BRD-K19601669 |
| Compound Name: | ruxolitinib-(S) |
| Targets: | JAK1|JAK2 |
| MoA: | JAK inhibitor |
| SMILES: | N#CC[C@@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121362 | BRD-K19601669 | A375 | 10 uM | 24 h | 0.35 | 1.45 | 1.12 | 0.0 | 0.0 | 0.0 |
| 121382 | BRD-K19601669 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.85 | 0.14 |
| 121436 | BRD-K19601669 | HT29 | 10 uM | 24 h | -0.28 | -1.16 | 0.45 | -0.2 | -0.68 | 0.02 |
| 121458 | BRD-K19601669 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121477 | BRD-K19601669 | PC3 | 10 uM | 24 h | -0.21 | -0.86 | 0.01 | 0.0 | 0.0 | 0.0 |
| 121504 | BRD-K19601669 | YAPC | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129463 | BRD-K19601669 | HELA | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |