CMap Candidate Details
Structure:
| CMap ID: | C04749 |
| Pert ID: | BRD-K46766488 |
| Compound Name: | S-14506 |
| Targets: | HTR1A |
| MoA: | serotonin receptor agonist |
| SMILES: | COc1ccc2cccc(N3CCN(CCNC(=O)c4ccc(F)cc4)CC3)c2c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 6757 | BRD-K46766488 | A375 | 10 uM | 24 h | 0.28 | 1.15 | 0.32 | 0.0 | 0.0 | 0.0 |
| 7158 | BRD-K46766488 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.28 | 1.0 | 0.42 |
| 7326 | BRD-K46766488 | HA1E | 10 uM | 24 h | -0.21 | -0.89 | 0.04 | 0.0 | 0.0 | 0.0 |
| 8001 | BRD-K46766488 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.35 | 1.22 | 1.18 |
| 8190 | BRD-K46766488 | MCF??7.00 | 10 uM | 6 h | 0.24 | 0.99 | 0.1 | 0.0 | 0.0 | 0.0 |
| 8374 | BRD-K46766488 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.15 | 1.07 |
| 8682 | BRD-K46766488 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.95 | 0.42 |
| 99571 | BRD-K46766488 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |