CMap Candidate Details
Structure:
| CMap ID: | C00475 |
| Pert ID: | BRD-A19795905 |
| Compound Name: | atovaquone |
| Targets: | DHODH |
| MoA: | mitochondrial electron transport inhibitor |
| SMILES: | Clc1ccc(cc1)[C@H]1CC[C@@H](CC1)C1C(=O)C(=O)c2ccccc2C1=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 91131 | BRD-A19795905 | HUH7 | 10 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121403 | BRD-A19795905 | HELA | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.01 | 0.57 |
| 121506 | BRD-A19795905 | YAPC | 3.33 uM | 24 h | 0.22 | 0.92 | 0.04 | -0.24 | -0.8 | 0.12 |
| 129401 | BRD-A19795905 | A375 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129431 | BRD-A19795905 | HA1E | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129487 | BRD-A19795905 | HT29 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129517 | BRD-A19795905 | MCF??7.00 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129550 | BRD-A19795905 | PC3 | 2.22 uM | 24 h | 0.36 | 1.5 | 1.43 | 0.0 | 0.0 | 0.0 |