CMap Candidate Details
Structure:
| CMap ID: | C04756 |
| Pert ID: | BRD-K93944989 |
| Compound Name: | safingol |
| Targets: | TRPM3 |
| MoA: | PKC inhibitor |
| SMILES: | CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CO |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 128380 | BRD-K93944989 | A549 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.36 | 1.27 | 1.34 |
| 128435 | BRD-K93944989 | HEK293 | 0.3 uM | 24 h | 0.24 | 1.0 | 0.11 | 0.0 | 0.0 | 0.0 |
| 128504 | BRD-K93944989 | HT29 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.19 | 1.15 |
| 128545 | BRD-K93944989 | JURKAT | 1.11 uM | 24 h | 0.22 | 0.93 | 0.05 | 0.0 | 0.0 | 0.0 |
| 128637 | BRD-K93944989 | MDAMB231 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128679 | BRD-K93944989 | PC3 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128717 | BRD-K93944989 | THP1 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 136177 | BRD-K93944989 | A375 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.88 | 0.26 |
| 136222 | BRD-K93944989 | HA1E | 0.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.28 | 0.98 | 0.38 |
| 136261 | BRD-K93944989 | HELA | 0.003 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 136310 | BRD-K93944989 | MCF10A | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 136342 | BRD-K93944989 | MCF??7.00 | 0.001 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 136384 | BRD-K93944989 | YAPC | 0.025 uM | 24 h | 0.29 | 1.21 | 0.46 | 0.25 | 0.89 | 0.21 |