CMap Candidate Details
Structure:
| CMap ID: | C00477 |
| Pert ID: | BRD-A75935363 |
| Compound Name: | atracurium |
| Targets: | CHRNA2 |
| MoA: | acetylcholine receptor antagonist |
| SMILES: | COc1ccc(CC2c3cc(OC)c(OC)cc3CC[N+]2(C)CCC(=O)OCCCCCOC(=O)CC[N+]2(C)CCc3cc(OC)c(OC)cc3C2Cc2ccc(OC)c(OC)c2)cc1OC |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24396 | BRD-A75935363 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.31 | 1.09 | 0.67 |
| 24541 | BRD-A75935363 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24855 | BRD-A75935363 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.27 | 0.97 | 0.35 |
| 25136 | BRD-A75935363 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25307 | BRD-A75935363 | VCAP | 10 uM | 24 h | 0.25 | 1.04 | 0.15 | -0.29 | -0.98 | 0.47 |
| 51257 | BRD-A75935363 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 91363 | BRD-A75935363 | HUH7 | 3.33 uM | 72 h | 0.47 | 1.96 | 15.65 | -0.29 | -0.97 | 0.45 |