CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04806
Pert ID:	BRD-K14807180
Compound Name:	SB-221284
Targets:	HTR2A\|HTR2B\|HTR2C
MoA:	serotonin receptor antagonist
SMILES:	CSc1cc2CCN(C(=O)Nc3cccnc3)c2cc1C(F)(F)F
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4065	BRD-K14807180	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
4371	BRD-K14807180	HCC515	10 uM	24 h	-0.24	-1.01	0.16	0.0	0.0	0.0
4651	BRD-K14807180	PC3	10 uM	24 h	0.0	0.0	0.0	-0.27	-0.91	0.29
5040	BRD-K14807180	VCAP	10 uM	6 h	0.0	0.0	0.0	-0.33	-1.11	0.92
44312	BRD-K14807180	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
44676	BRD-K14807180	A549	10 uM	6 h	-0.26	-1.1	0.34	-0.35	-1.19	1.15
44866	BRD-K14807180	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
45170	BRD-K14807180	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45439	BRD-K14807180	HT29	10 uM	6 h	0.0	0.0	0.0	-0.24	-0.82	0.14
45656	BRD-K14807180	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.23	0.82	0.1
45981	BRD-K14807180	NPC	10 uM	24 h	0.0	0.0	0.0	-0.28	-0.95	0.4
46300	BRD-K14807180	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46617	BRD-K14807180	SKB	10 uM	24 h	0.0	0.0	0.0	-0.3	-1.02	0.6
100123	BRD-K14807180	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary