CMap Candidate Details
Structure:
| CMap ID: | C04810 |
| Pert ID: | BRD-K98795921 |
| Compound Name: | SB-2343 |
| Targets: | MTOR|PIK3CA|PIK3CB|PIK3CD|PIK3CG |
| MoA: | mTOR inhibitor; PI3K inhibitor |
| SMILES: | CC(C)n1c(C)nc2c(nc(nc12)N1CCOCC1)-c1cnc(N)nc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 87282 | BRD-K98795921 | BJAB | 2.5 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 87336 | BRD-K98795921 | HBL1 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 87384 | BRD-K98795921 | K562 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.21 | 0.74 | 0.04 |
| 87433 | BRD-K98795921 | KMS34 | 0.66 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 87481 | BRD-K98795921 | MINO | 2.5 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.19 | -0.62 | 0.0 |
| 87536 | BRD-K98795921 | NALM6 | 2.5 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 87586 | BRD-K98795921 | OCILY10 | 2.5 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 87638 | BRD-K98795921 | OCILY19 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.07 | 0.76 |
| 87686 | BRD-K98795921 | OCILY3 | 2.5 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.17 | -0.59 | 0.0 |
| 87737 | BRD-K98795921 | SKMEL5 | 2.5 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 87811 | BRD-K98795921 | THP1 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.18 | 0.64 | 0.0 |
| 87841 | BRD-K98795921 | TMD8 | 10 uM | 3 h | 0.0 | 0.0 | 0.0 | -0.22 | -0.76 | 0.07 |