CMap Candidate Details
Structure:
| CMap ID: | C00482 |
| Pert ID: | BRD-K58435339 |
| Compound Name: | AT13387 |
| Targets: | HSP90AA1 |
| MoA: | HSP antagonist |
| SMILES: | CC(C)c1cc(C(=O)N2Cc3ccc(CN4CCN(C)CC4)cc3C2)c(O)cc1O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 123536 | BRD-K58435339 | HA1E | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.92 | 0.33 |
| 123568 | BRD-K58435339 | HEK293 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123644 | BRD-K58435339 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123685 | BRD-K58435339 | MCF10A | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123763 | BRD-K58435339 | YAPC | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.28 | 1.0 | 0.42 |
| 131977 | BRD-K58435339 | A375 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132033 | BRD-K58435339 | HELA | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.35 | 1.23 | 1.19 |
| 132077 | BRD-K58435339 | MCF??7.00 | 0.08 uM | 24 h | -0.25 | -1.04 | 0.21 | -0.29 | -0.97 | 0.46 |
| 132108 | BRD-K58435339 | PC3 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |