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CMap Candidate Details

Structure:
CMap ID: C04825
Pert ID: BRD-K67298865
Compound Name: SB-431542
Targets: ACVR1C|TGFBR1
MoA: TGF beta receptor inhibitor
SMILES: NC(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccccn1)-c1ccc2OCOc2c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2916 BRD-K67298865 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3250 BRD-K67298865 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3850 BRD-K67298865 VCAP 10 uM 24 h -0.24 -0.99 0.14 0.0 0.0 0.0
42131 BRD-K67298865 A549 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.2 1.19
42444 BRD-K67298865 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42758 BRD-K67298865 HEPG2 10 uM 6 h -0.25 -1.03 0.2 0.0 0.0 0.0
43056 BRD-K67298865 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43225 BRD-K67298865 MCF??7.00 10 uM 24 h 0.25 1.04 0.15 -0.24 -0.81 0.13
43623 BRD-K67298865 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43925 BRD-K67298865 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44179 BRD-K67298865 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96734 BRD-K67298865 A375 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.08
96786 BRD-K67298865 PC3 10 uM 24 h 0.27 1.12 0.27 -0.27 -0.89 0.27
99365 BRD-K67298865 U2OS 12.5 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).