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CMap Candidate Details

Structure:
CMap ID: C04833
Pert ID: BRD-K65991129
Compound Name: SB-705498
Targets: TRPV1
MoA: TRPV antagonist
SMILES: FC(F)(F)c1ccc(nc1)N1CC[C@H](C1)NC(=O)Nc1ccccc1Br
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96341 BRD-K65991129 A375 10 uM 24 h -0.26 -1.07 0.27 0.22 0.76 0.05
96411 BRD-K65991129 PC3 1.11 uM 24 h 0.28 1.18 0.39 0.0 0.0 0.0
124600 BRD-K65991129 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124620 BRD-K65991129 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
124640 BRD-K65991129 HEK293 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
124697 BRD-K65991129 HT29 10 uM 24 h 0.24 1.0 0.11 -0.36 -1.23 1.25
124727 BRD-K65991129 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124744 BRD-K65991129 MCF10A 1.11 uM 24 h -0.22 -0.93 0.07 0.31 1.11 0.72
124764 BRD-K65991129 MCF??7.00 10 uM 24 h 0.27 1.15 0.32 0.0 0.0 0.0
124885 BRD-K65991129 THP1 0.04 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
132791 BRD-K65991129 HELA 0.74 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
132918 BRD-K65991129 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.33 1.18 0.98
132956 BRD-K65991129 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).