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CMap Candidate Details

Structure:
CMap ID: C04840
Pert ID: BRD-K86797399
Compound Name: SB-939
Targets: HDAC1|HDAC10|HDAC3|HDAC4|HDAC5|HDAC9
MoA: HDAC inhibitor
SMILES: CCCCc1nc2cc(ccc2n1CCN(CC)CC)\C=C\C(=O)NO
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
93658 BRD-K86797399 ASC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93720 BRD-K86797399 CD34 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93797 BRD-K86797399 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93931 BRD-K86797399 HEPG2 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
93965 BRD-K86797399 HUVEC 0.12 uM 24 h 0.0 0.0 0.0 -0.21 -0.72 0.04
94109 BRD-K86797399 NEU 1.11 uM 24 h 0.21 0.89 0.02 0.28 0.97 0.36
94178 BRD-K86797399 NPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94243 BRD-K86797399 SHSY5Y 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94295 BRD-K86797399 SKL 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125972 BRD-K86797399 A375 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126063 BRD-K86797399 HT29 0.125 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.01
126155 BRD-K86797399 JURKAT 0.37 uM 24 h -0.26 -1.08 0.29 0.0 0.0 0.0
126206 BRD-K86797399 MCF10A 1.11 uM 24 h -0.19 -0.8 0.0 -0.35 -1.19 1.15
126225 BRD-K86797399 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 -0.21 -0.72 0.04
126248 BRD-K86797399 MDAMB231 1.11 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
126276 BRD-K86797399 PC3 0.37 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
126325 BRD-K86797399 THP1 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134054 BRD-K86797399 A549 0.25 uM 24 h 0.0 0.0 0.0 0.19 0.66 0.01
134077 BRD-K86797399 HA1E 0.08 uM 24 h 0.34 1.4 1.02 0.0 0.0 0.0
134129 BRD-K86797399 HEK293 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134168 BRD-K86797399 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134331 BRD-K86797399 YAPC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).