CMap Candidate Details
Structure:
| CMap ID: | C04844 |
| Pert ID: | BRD-K40797222 |
| Compound Name: | SC-12267 |
| Targets: | IL17A |
| MoA: | dihydroorotate dehydrogenase inhibitor |
| SMILES: | COc1cccc(c1)-c1ccc(NC(=O)C2=C(CCC2)C(O)=O)c(F)c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 123547 | BRD-K40797222 | HA1E | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123599 | BRD-K40797222 | HEK293 | 10 uM | 24 h | 0.25 | 1.06 | 0.19 | 0.35 | 1.24 | 1.24 |
| 123631 | BRD-K40797222 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.4 | 1.43 | 2.2 |
| 123666 | BRD-K40797222 | HT29 | 3.33 uM | 24 h | -0.22 | -0.92 | 0.06 | 0.34 | 1.2 | 1.12 |
| 123714 | BRD-K40797222 | MCF10A | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123734 | BRD-K40797222 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123751 | BRD-K40797222 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.91 | 0.24 |
| 123778 | BRD-K40797222 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.21 | -0.72 | 0.04 |
| 131999 | BRD-K40797222 | A375 | 2.22 uM | 24 h | 0.26 | 1.07 | 0.2 | 0.0 | 0.0 | 0.0 |