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CMap Candidate Details

Structure:
CMap ID: C04849
Pert ID: BRD-K14767410
Compound Name: SC-560
Targets: PTGS1
MoA: cyclooxygenase inhibitor
SMILES: COc1ccc(cc1)-n1nc(cc1-c1ccc(Cl)cc1)C(F)(F)F
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4196 BRD-K14767410 HA1E 10 uM 6 h -0.22 -0.9 0.04 -0.28 -0.95 0.41
4370 BRD-K14767410 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4780 BRD-K14767410 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4899 BRD-K14767410 VCAP 10 uM 24 h 0.0 0.0 0.0 0.31 1.08 0.65
44311 BRD-K14767410 A375 10 uM 6 h 0.0 0.0 0.0 0.29 1.01 0.45
44525 BRD-K14767410 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44865 BRD-K14767410 ASC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
45169 BRD-K14767410 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45438 BRD-K14767410 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45655 BRD-K14767410 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45980 BRD-K14767410 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46616 BRD-K14767410 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).