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CMap Candidate Details

Structure:
CMap ID: C04856
Pert ID: BRD-K81225797
Compound Name: SCH-58261
Targets: ADORA1|ADORA2A|ADORA2B|ADORA3
MoA: adenosine receptor antagonist
SMILES: Nc1nc2n(CCc3ccccc3)ncc2c2nc(nn12)-c1ccco1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1636 BRD-K81225797 HA1E 10 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.19
2129 BRD-K81225797 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2429 BRD-K81225797 PC3 10 uM 6 h 0.0 0.0 0.0 0.34 1.21 1.15
2630 BRD-K81225797 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41848 BRD-K81225797 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41983 BRD-K81225797 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42482 BRD-K81225797 ASC 10 uM 24 h 0.28 1.18 0.39 0.0 0.0 0.0
42792 BRD-K81225797 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43085 BRD-K81225797 HT29 10 uM 6 h 0.0 0.0 0.0 0.33 1.17 0.92
43240 BRD-K81225797 MCF??7.00 10 uM 24 h 0.24 1.02 0.13 0.23 0.83 0.11
43657 BRD-K81225797 NPC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
43959 BRD-K81225797 PHH 10 uM 24 h 0.19 0.81 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).