CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04865
Pert ID:	BRD-A49906757
Compound Name:	scopolamine-n-oxide
Targets:	CHRM1\|CHRM2\|CHRM3\|CHRM4\|CHRM5\|SI
MoA:	acetylcholine receptor antagonist
SMILES:	C[N+]1([O-])[C@H]2C[C@@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1697	BRD-A49906757	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
1832	BRD-A49906757	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
2341	BRD-A49906757	PC3	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
2695	BRD-A49906757	VCAP	10 uM	6 h	0.0	0.0	0.0	-0.32	-1.06	0.74
41674	BRD-A49906757	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
42016	BRD-A49906757	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
42214	BRD-A49906757	ASC	10 uM	24 h	0.25	1.04	0.14	-0.31	-1.04	0.68
42556	BRD-A49906757	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
42864	BRD-A49906757	HT29	10 uM	6 h	0.31	1.28	0.64	0.0	0.0	0.0
43128	BRD-A49906757	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	-0.29	-0.96	0.43
43415	BRD-A49906757	NPC	10 uM	24 h	0.0	0.0	0.0	-0.41	-1.38	2.02
43725	BRD-A49906757	PHH	10 uM	24 h	0.0	0.0	0.0	-0.23	-0.76	0.07
44014	BRD-A49906757	SKB	10 uM	24 h	0.0	0.0	0.0	0.25	0.88	0.18
100195	BRD-A49906757	U2OS	4 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary