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CMap Candidate Details

Structure:
CMap ID: C04876
Pert ID: BRD-K15868788
Compound Name: SDZ-205-557
Targets: HTR3A|HTR3B
MoA: serotonin receptor antagonist
SMILES: CCN(CC)CCOC(=O)c1cc(Cl)c(N)cc1OC
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2987 BRD-K15868788 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3335 BRD-K15868788 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3597 BRD-K15868788 PC3 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.25 1.35
3944 BRD-K15868788 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39094 BRD-K15868788 A375 10 uM 6 h -0.23 -0.94 0.08 0.0 0.0 0.0
39429 BRD-K15868788 A549 10 uM 6 h -0.22 -0.91 0.05 0.0 0.0 0.0
39633 BRD-K15868788 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39949 BRD-K15868788 HEPG2 10 uM 6 h -0.31 -1.29 0.79 0.25 0.87 0.18
40231 BRD-K15868788 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40453 BRD-K15868788 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40757 BRD-K15868788 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41057 BRD-K15868788 NPC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.52
41386 BRD-K15868788 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).