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CMap Candidate Details

Structure:
CMap ID: C04877
Pert ID: BRD-A15530910
Compound Name: SDZ-21009
Targets: HTR1A|HTR1B
MoA: adrenergic receptor antagonist; serotonin receptor antagonist
SMILES: CC(C)OC(=O)c1cc2c(OCC(O)CNC(C)(C)C)cccc2[nH]1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1482 BRD-A15530910 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1812 BRD-A15530910 HCC515 10 uM 24 h 0.0 0.0 0.0 0.32 1.15 0.88
2319 BRD-A15530910 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2592 BRD-A15530910 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.14
41648 BRD-A15530910 A375 10 uM 6 h -0.31 -1.31 0.82 -0.24 -0.79 0.11
41872 BRD-A15530910 A549 10 uM 24 h 0.0 0.0 0.0 0.44 1.56 2.33
42179 BRD-A15530910 ASC 10 uM 24 h 0.23 0.96 0.07 0.0 0.0 0.0
42524 BRD-A15530910 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.32 1.14 0.87
42833 BRD-A15530910 HT29 10 uM 6 h 0.25 1.04 0.15 0.37 1.32 1.71
43113 BRD-A15530910 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43380 BRD-A15530910 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43696 BRD-A15530910 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43993 BRD-A15530910 SKB 10 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.5
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).