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CMap Candidate Details

Structure:
CMap ID: C04883
Pert ID: BRD-A70083328
Compound Name: secnidazole
Targets:
MoA: acetylcholinesterase inhibitor; microtubule inhibitor
SMILES: CC(O)Cn1c(C)ncc1[N+]([O-])=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25306 BRD-A70083328 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91453 BRD-A70083328 HUH7 20 uM 72 h 0.0 0.0 0.0 0.24 0.84 0.13
100300 BRD-A70083328 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
126776 BRD-A70083328 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
126837 BRD-A70083328 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126883 BRD-A70083328 MDAMB231 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126948 BRD-A70083328 THP1 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126993 BRD-A70083328 YAPC 0.37 uM 24 h 0.18 0.74 0.0 0.34 1.19 1.05
134675 BRD-A70083328 A375 0.08 uM 24 h -0.27 -1.14 0.43 0.0 0.0 0.0
134698 BRD-A70083328 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134727 BRD-A70083328 HA1E 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134764 BRD-A70083328 HEK293 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134796 BRD-A70083328 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134824 BRD-A70083328 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134863 BRD-A70083328 HUVEC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134925 BRD-A70083328 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
134963 BRD-A70083328 PC3 0.08 uM 24 h 0.0 0.0 0.0 0.26 0.9 0.23
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).