CMap Candidate Details
Structure:
| CMap ID: | C04886 |
| Pert ID: | BRD-K49071277 |
| Compound Name: | securinine |
| Targets: | GABRA1 |
| MoA: | GABA receptor antagonist; TP53 activator |
| SMILES: | O=C1O[C@@]23C[C@@H](C=CC2=C1)N1CCCC[C@H]31 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1009 | BRD-K49071277 | CD34 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 1047 | BRD-K49071277 | HL60 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 1079 | BRD-K49071277 | PC3 | 0.37 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 1104 | BRD-K49071277 | U937 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |