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CMap Candidate Details

Structure:
CMap ID: C04887
Pert ID: BRD-A58564983
Compound Name: selamectin
Targets:
MoA: nematocide
SMILES: CO[C@H]1CC(O[C@H]2[C@@H](C)\C=C\C=C3/CO[C@@H]4C(=N/O)\C(C)=C[C@@H](C(=O)O[C@H]5C[C@@H](C\C=C2/C)O[C@@]2(CC[C@H](C)[C@H](O2)C2CCCCC2)C5)[C@]34O)O[C@@H](C)C1O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5407 BRD-A58564983 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5533 BRD-A58564983 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.71 0.03
5849 BRD-A58564983 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6139 BRD-A58564983 PC3 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
6354 BRD-A58564983 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37089 BRD-A58564983 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37525 BRD-A58564983 ASC 10 uM 24 h -0.2 -0.83 0.0 0.0 0.0 0.0
38651 BRD-A58564983 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123843 BRD-A58564983 A549 10 uM 24 h -0.31 -1.3 0.81 0.0 0.0 0.0
123909 BRD-A58564983 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123948 BRD-A58564983 HELA 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124010 BRD-A58564983 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124063 BRD-A58564983 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.86
124099 BRD-A58564983 MCF??7.00 10 uM 24 h 0.29 1.22 0.48 0.31 1.09 0.68
124131 BRD-A58564983 MDAMB231 10 uM 24 h 0.0 0.0 0.0 -0.42 -1.41 2.02
124192 BRD-A58564983 THP1 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124244 BRD-A58564983 YAPC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132233 BRD-A58564983 HT29 0.25 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.03
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).